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Boehringer Ingelheim
The epidermal growth factor receptor (EGFR) family is a group of receptors implicated in the development of NSCLC. The EGFR family consists of four membrane-bound receptor tyrosine kinases (RTK), which include EGFR, HER2, HER3, HER4. In many cancers, such as NSCLC, members of the EGFR family are often overexpressed and can provide an oncogenic signal.
Source for healthcare professionals: www.inoncology.com
* Nintedanib (BIBF 1120), afatinib (BIBW 2992) and volasertib (BI 6727) are investigational compounds. Their safety and efficacy have not yet been fully established.
