The White Room
Pathways in EGFR and HER signaling
Download now

Add to my Selection



Size: 0.16 MB (JPG)
Rating:

Pathways in EGFR and HER signaling

Boehringer Ingelheim

 

Activation of homodimeric EGFR or heterodimeric HER2/HER3 or EGFR/HER2 by ligand-binding leads to downstream signaling that converges in three main pathways:

  1. PI3K/AKT pathway
  2. STAT pathway
  3. RAS/MAPK pathway

 


Related Documents

Items: 10
Irreversible binding of afatinib

Irreversible binding of afatinib

BIBW 2992 cancer treatment data presented at ASCO

BIBW 2992 cancer treatment data presented at ASCO

Press release Lux phase 3 BIBW 2992 (afatinib)

Press release Lux phase 3 BIBW 2992 (afatinib)

LUX-Lung Clinical Trial Programme

LUX-Lung Clinical Trial Programme

LUX Lung 2 clinical trial

LUX Lung 2 clinical trial

LUME-Ovar 1 ovarian cancer clinical trial

LUME-Ovar 1 ovarian cancer clinical trial

Mutation detection with Quantitative Real Time PCR (Q-PCR)

Mutation detection with Quantitative Real Time PCR (Q-PCR)

Head and Neck Cancer Infographic

Head and Neck Cancer Infographic

The latest data for BIBF 1120* in ovarian cancer

The latest data for BIBF 1120* in ovarian cancer

BIBF 1120 anticancer agent

BIBF 1120 anticancer agent